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3/6/2021

Combating COVID-19 Vaccine  Misinformation

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PictureCOVID-19 Vaccine
We have begun to detect early signs that COVID-19 vaccination is having a dramatic effect in reducing the number of new cases and deaths. This data comes from studies performed in nursing homes where the vaccine was made available first. Despite this good news, there is a substantial amount of misinformation about the COVID-19 vaccine that is stoking doubt among people that would otherwise elect to be vaccinated. In this post I will address some of these claims.
 
Vaccine development is a process that takes a decade or more. The COVID-19 vaccines were developed in a year (Operation Warp Speed), so they were rushed, therefore there is no way they can be safe.
This claim reveals a misunderstanding of what Operation Warp Speed did. This vaccine development operation was not fast because they cut corners. There are several reasons vaccine development was fast, but one of the most important ones was that the government funded multiple stages of the vaccine development process at once. For example, the vaccine was produced at the same time the clinical trials were ongoing. A pharmaceutical company normally waits for the results of the trials before producing the vaccine, because if the trial fails, then it would lose all the investment in producing a vaccine that wouldn’t be approved. In Operation Warp Speed it was the government that assumed this economic risk, and this accelerated the pace of vaccine production. No corners were cut in the development process. The vaccines were tested in regular clinical trials and they were found to be effective and safe.
 
The coronavirus is a new virus and the Moderna and Pfizer messenger RNA (mRNA) vaccines are a new technology. There is no way that a new technology can be applied to a new virus and result in a safe vaccine in such a short time.
This claim ignores the history of both the involvement of scientists with coronaviruses and the history of the development of the mRNA technology. Scientists had been researching coronaviruses such as SARS (2003) and MERS (2012) for many years. By studying these and other viruses they discovered how the proteins in the surface of the virus change when attacking a cell, and they figured out how to make antibodies to the right proteins to avoid problems that can compromise a vaccine. The mRNA technology they used had also been researched for decades and had reached its full potential by the time COVID-19 came around. Finally the Johnson and Johnson vaccine is also as effective and safe as the others and is not based on mRNA technology.
 
The mRNA vaccines will change your DNA, and can give you COVID-19.
This is not how mRNA works. DNA produces mRNA, and mRNA carries the instructions for the production of proteins. However, mRNA cannot go back to DNA and alter it. If I asked you whether you are concerned that while you are walking on the sidewalk the concrete under your feet will turn into quicksand and swallow you up, you would probably reply that is silly because it’s not in the nature of concrete to do that. Similarly, it is not in the nature of mRNA to alter DNA. The SARS-Cov-2 virus that produces COVID-19 has a total of 29 proteins. The vaccines contain an mRNA molecule that carries the information to produce ONLY ONE viral protein (the spike protein that the virus uses to enter the cells). The body then produces antibodies against this protein, and the mRNA is degraded after a few hours. The mRNA does not carry the information to produce the rest of the proteins of the virus, thus it is impossible for the mRNA vaccine to give you COVID-19.
 
They tell us that after we get vaccinated, we still need to wear a mask and social distance, so why get vaccinated at all?
It is not known if the vaccine can prevent you from being infected with the virus. What we know is that the vaccine will help you fight the virus and protect you against moderate and severe COVID-19 disease. However, scientists don’t know if vaccinated people are still capable of carrying the virus and transmitting it to other people. Thus, scientists are just being careful and recommending that vaccinated people still use masks and social distance while in the presence of others that may not yet be vaccinated until they can answer this question.
 
The COVID-19 vaccines have side effects and have caused severe allergic reactions.
The side effects of the COVID-19 vaccines are an indication that the immune system is working. These side effects, such as pain at the site of injection, fatigue, headache, and muscle pain, normally last 24 hours and are an acceptable tradeoff for gaining immunity against a disease that can potentially be lethal or debilitating to you and others you may transmit it to. In rare cases an allergic reaction to the vaccine has been documented which mostly occurs within 30 minutes of vaccination and can be treated by the medical personnel administering the vaccine. This is why it is recommended that people who have a history of allergic reactions should consult with their doctors before getting the vaccine.
 
The COVID-19 vaccines have caused several deaths.
This piece of misinformation is straight out of the antivaxxer playbook, and it is based on claims that people who died or had a problem after receiving a vaccine died or had the problem because of the vaccine. In a population of millions of individuals, thousands of people naturally die or have health issues every day. If millions of people get a vaccine, some of them will naturally die or have health issues around the time they received the vaccine, but in a manner unrelated to the vaccine. In other words: correlation does not imply causation. So far the alleged vaccine deaths that have been investigated have not been linked to the vaccine.
 
More than 500,000 American have died as a result of COVID-19 and tens of thousands have been left with long-lasting side effects. All this could have been avoided if we had had a vaccine for the disease at the begining. Well, now we have 3 vaccines against the disease (not counting the Russian, Indian, and Chinese vaccines). There are still tens of millions of people in the US who have not yet had COVID-19, and therefore there is potential for additional morbidity and mortality from the disease. It is important for everyone to get vaccinated to protect both themselves and those around them, so please don’t fall for the vaccine misinformation. Get vaccinated.
 

The photo of the COVID-19 vaccine by Lisa Ferdinando (DOD) was taken from the Flickr photostream of the US Secretary of Defense and is used here under an Attribution 2.0 Generic (CC BY 2.0) license.

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